Improving Analysis of Quality Indicating Attributes for Better Lifecycle Management

Library Number:
PSTR135120016
Author(s):
Robert Birdsall, Kellen DeLaney, Pawel Bigos, Tatyana Friedman
Source:
Waters
Content Type:
Posters
Content Subtype:
Other Symposium
Related Products:
 
ACQUITY QDa Detector - Effortless Integration
 
 

As part of lifecycle management, ICH guidance recommends identifying and evaluating opportunities to improve drug safety and continually expand the body of knowledge in the manufacturing of drug products. In this study, we demonstrate increased recovery and sensitivity for quality indicating attributes in a RPLC peptide mapping assay using an LC and column engineered with modified bioinert hardware while preserving compatibility with legacy methods to facilitate easier method migration.


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