QuanRecovery HPS Vials & Plates

QuanRecovery Vials and Plates

Reduce sample losses due to non-specific binding (NSB)

Reduce sample losses due to non-specific binding (NSB)

Successfully quantitating proteins and peptides with LC–MS is often more challenging than doing so for small molecules. Their large and complex structure requires a different approach to LC–MS method development and may also cause other unique problems like nonspecific adsorption (or nonspecific binding). Proteins and peptides in solution tend to stick to the surfaces they encounter.

Autosampler-ready QuanRecovery Vials and Plates with MaxPeak High Performance Surfaces (HPS) are designed to enable scientists like you to meet recovery, sensitivity and reproducibility challenges in LC-MS peptide and protein quantification. By reducing sample losses from non-specific binding (NSB) and ionic interactions, QuanRecovery Vials and Plates provide your lab greater confidence in analytical results and fewer long-term assay repeatability problems.

QuanRecovery Vials & Plates with MaxPeak HPS. QuanRecovery Vials and Plates
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Specifications

Overview

  • For large molecule LC-MS bioanalysts who need the ultimate sensitivity, reproducibility and sample stability over multiple analyses.
  • Improve detection limits and analysis reproducibility for peptide and protein quantification with these low adsorption plates and vials.
  • Designed for LC-MS analysis in autosampler ready formats with low residual volumes in 700 µL 96-well plate and 300 µL sample vial formats.
  • Increase analyte recovery, sensitivity and reproducibility by minimizing analyte/surface interactions that can lead to sample losses with MaxPeak High Performance Surfaces (HPS).
  • Suitable for workflows with ACQUITY Premier Systems and Columns.

Recommended Use: To minimize sample losses due to non-specific binding (NSB) and ionic interactions.

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Improved LC-MS analysis of peptides and proteins

It can be difficult to predict peptide losses due to non-specific binding and ionic interactions, as losses can be dependent on many characteristics, including pI and hydrophobicity. Demonstrated here are the recovery of four different peptides. The recovery of desmopressin is not affected by the sample container, while glucagon, insulin, and melittin suffer varying losses due to non-specific binding and ionic interactions in the glass and standard polypropylene containers. 

Only QuanRecovery Vials and Plates with MaxPeak HPS protect these peptides from loss, enabling you to achieve higher recovery and improved repeatability.

Enhanced recovery and sensitivity at high and low sample concentrations

Biomolecule sample losses are a problem at low concentrations. However, non-specific binding and ionic interactions can also cause losses at higher concentrations. Such losses not only negatively impact the assay sensitivity, they also compromise the reproducibility, precision, and accuracy of the analysis. QuanRecovery Vials and Plates with MaxPeak HPS protect your sample, ensuring improved analytical results.

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QuanRecovery HPS Vials & Plates are specialized laboratory items crafted for use in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) applications. These vials and plates are optimized to ensure the precise and sensitive quantification of analytes within samples.

Here are few characteristics of QuanRecovery HPS Vials & Plates may encompass:

Superior Materials: Typically constructed from high-quality materials, such as glass or polymer, to safeguard sample integrity and minimize analyte adsorption or contamination.

Exact Design: These vials and plates are meticulously engineered to meet the exacting demands of analytical chemistry, delivering consistent and dependable outcomes.

Reduced Surface Interactions: They may feature a coating or treatment with low surface activity to diminish interactions between analytes and surfaces.

Versatility: QuanRecovery HPS Vials & Plates are designed to be compatible with a variety of HPLC and MS instruments, seamlessly fitting into analytical workflows.

Sample Safeguarding: They might incorporate features like septa or caps, safeguarding samples against environmental contamination and evaporation.

Varied Options: QuanRecovery offers a wide selection of vial sizes, plate formats, and supplementary accessories to cater to diverse research requirements and sample volumes.

Precision and Sensitivity: These products are particularly well-suited for quantitative analyses where precision and sensitivity hold paramount importance, as seen in pharmaceutical research, environmental monitoring, and clinical diagnostics.

QuanRecovery HPS Vials & Plates stand as specialized laboratory consumables tailored to fulfill the rigorous demands of analytical chemistry, ensuring the precise and dependable quantification of analytes in a range of applications. Their top-quality materials and precise design render them invaluable assets within the realms of chromatography and mass spectrometry.

Applications of QuanRecovery HPS Vials & Plates

QuanRecovery HPS Vials & Plates find extensive applications in analytical chemistry, pharmaceuticals, environmental science, clinical diagnostics, life sciences, and multiple industries. They are crucial for HPLC analysis, enabling compound separation and quantification in pharmaceutical quality control and environmental monitoring. Compatible with mass spectrometry, they support precise analyte identification in proteomics, metabolomics, and drug discovery. In pharmaceutical research, they facilitate drug compound analysis, ensuring regulatory compliance. Additionally, these consumables are instrumental in clinical diagnostics, life sciences research, chemical analysis, biotechnology, quality control, and academic research, ensuring accurate quantification and analysis in diverse research and industrial contexts.

QuanRecovery HPS Vials & Plates

1.What are the available sizes and formats of QuanRecovery HPS Vials & Plates?
QuanRecovery HPS Vials & Plates come in a variety of sizes and formats to meet different sample volumes and analytical requirements. For vials, options include sizes like 1.5 mL, 2.0 mL, and larger volumes depending on your needs. For high-throughput applications, plates are available in both 96-well and 384-well formats. Custom formats may be available upon request to address specific laboratory needs, offering flexibility for specialized applications.

2.What is the maximum operating temperature for QuanRecovery HPS Vials & Plates?
The maximum operating temperature for QuanRecovery HPS Vials & Plates varies based on the specific product and intended application. Generally, these vials and plates are designed to withstand typical temperatures encountered in analytical labs, including those used for sample preparation, storage, and analysis. It's always a good idea to consult the specific product's guidelines to ensure safe operation within the recommended temperature range for optimal performance.

3.Are there any special handling or storage requirements for QuanRecovery HPS Vials & Plates?
Proper handling and storage are key to maintaining the performance and longevity of QuanRecovery HPS Vials & Plates. To prevent contamination, it's important to handle them carefully and avoid contact with dust, fingerprints, or other contaminants. They should be stored in a clean, dry environment, away from direct sunlight and extreme temperatures. In addition, caution should be exercised when inserting or removing inserts or septa to avoid damage. For best results, always follow the specific handling and storage recommendations for each product.