Laboratory Filters

Laboratory Filters

The right lab filter for any sample type

The right lab filter for any sample type

Sample and solvent filtration is a preventative maintenance procedure that saves labs time and money. Laboratory filtration products can help minimize downtime by providing immediate protection for the column and instrumentation components. With Pall Life Sciences Filters from Waters, you can confidently meet your regulatory and quality objectives with lab filters that have been designed, developed, and certified for compliance.

With our broad range of Pall laboratory filters, your lab can access a range of different membranes for solvent and sample compatibility, as well as a variety of devices for various filtration applications. To choose the right filter for your lab, consider sample characteristics, volume, and pore size, then decide if the sample may require prefiltration because it is laden with particulate matter.

The broad range of Pall Life Sciences laboratory filter device sizes ensures complete sample filtration with minimal sample loss. Laboratory Filters
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Specifications

Overview

  • Save money and prevent downtime due to contamination with HPLC sample filters in syringe filter format
  • Achieve solvent and sample compatibility with HPLC solvent filters in membrane disc format
  • Easily perform vacuum filtration of liquids and degassing of HPLC solvent and mobile phases with the solvent filtration apparatus

Recommended Use: Pall Laboratory products are designed for laboratory applications only. These products are not approved for use in medical, clinical, surgical, or other patient applications.

Laboratory Filter Membrane Choices

Laboratory Filter Membrane Choices
Acrodisc MS wwPTFE Syringe Filters
  • Designed specifically to extend the lifespan of LC columns used for LC-MS analyses without adding significant extractables and with minimal analyte adsorption
  • Constructed with a water-wettable polytetrafluoroethylene (wwPTFE) membrane in high density polyethylene (HDPE) housings
wwPTFE Acrodiscs
  • All-purpose water wettable, hydrophilic, polytetrafluoroethylene membranes
  • Designed for aqueous, acidic, basic, non-aggressive organic, and aggressive organic solutions
  • Offers low protein binding and low levels of UV-absorbing extractables
Nylon Acrodiscs
  • Hydrophilic membrane that works well with both aqueous and organic solvents
  • Particularly suitable for high-pH samples but should be avoided in any protein recovery applications
wwPTFE Acrodisc GF and Nylon Acrodisc GF
  • Designed with a glass fiber prefilter over the membrane for hard to filter samples laden with particulate matter
Glass Fiber (GF) Acrodiscs
  • Can be used alone or as a prefilter with another Acrodisc in series
Acrodisc PVDF (LC)
  • Hydrophilic polyvinylidene fluoride (PVDF) membranes good for aqueous and organic solvents
Acrodisc PTFE (CR)
  • Hydrophobic, polytetrafluoroethylene (PTFE) membranes recommended for use with non-aqueous solvents
  • Organic-based, highly acidic or basic samples and solvents
Supor PES (IC) Filters for Ion Chromatography
  • Polyethersulfone (PES) IC filters are certified to contain low ionic backgrounds for ion chromatography

Concerned about particulate matter in your sample?

Concerned about particulate matter in your sample?

Step 1: Determine the nature of your sample

Identifying the right lab filter is a 3-step process. Begin selecting your lab filter by determining the nature of your sample with the guidelines below:

  • Aqueous: wwPTFE, Nylon, PVDF, and Supor PES
  • Non Polar: CR/PTFE, wwPTFE, and MS PTFE
  • Protein: wwPTFE and GH PVDF
  • Ion Chromatography: Supor PES

Step 2: Identify your column particle size

The micron size of the particles in your column matter. After determining your sample nature, match your column to the filter with these guidelines:

  • Micron size >3 µm: filter pore size of 0.45 µm - HPLC

  • Micron size <3 µm: filter pore size of 0.20 µm - UPLC

Step 3: Determine your sample volume

Finally, consider the volume of your sample to identify the right lab filter for your needs.

  •  Sample volume <2 mL: 4 mm filter and <10 µL hold up volume
  •  Sample volume <10 mL: 13 mm minispike and <14 µL hold up volume
  •  Sample volume <10 mL: 13 mm male Luer and <30 µL hold up volume
  •  Sample volume <100 mL: 25 mm filter and <100 µL hold up volume

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Laboratory Filters

Waters offers a wide range of Pall Life Sciences Filters designed to meet the filtration needs of diverse sample types while ensuring regulatory compliance, and labs save time and money by minimizing downtime and protecting equipment. These high-quality filters are essential for laboratories aiming to achieve accurate, reliable results and prolong the lifespan of valuable instrumentation components like HPLC columns.

When choosing the right laboratory filter, it's important to consider factors such as sample characteristics, volume, and pore size. If your sample contains high levels of particulate matter, prefiltration may be required to ensure effective filtration and protect downstream processes. With Pall laboratory filters, labs can access a variety of membranes designed to handle both solvent and sample filtration needs. These filters are available in different formats, including syringe filters for sample filtration and membrane disc filters for solvent compatibility, offering flexibility for a range of applications.

Pall's Acrodisc MS wwPTFE Syringe Filters are specifically designed to extend the lifespan of LC columns used in LC-MS analyses. These filters feature a water-wettable polytetrafluoroethylene (wwPTFE) membrane encased in high-density polyethylene (HDPE) housings. They are ideal for use with both aqueous and organic solvents, delivering excellent compatibility while minimizing the risk of extractables and analyte adsorption. This makes them a valuable choice for labs looking to improve the efficiency and accuracy of their LC-MS analyses.

For labs requiring filtration of aqueous, acidic, or basic solutions, Pall's all-purpose wwPTFE Acrodiscs offer a hydrophilic membrane that performs well across a variety of solvents. These filters are known for their low protein binding and minimal UV-absorbing extractables, making them versatile and reliable for a wide range of filtration needs. Similarly, the Nylon Acrodiscs provide a hydrophilic membrane that works effectively with both aqueous and organic solvents, especially high-pH samples. However, they are not recommended for protein recovery applications due to their interaction with proteins.

For samples that are difficult to filter due to high particulate content, the wwPTFE Acrodisc GF and Nylon Acrodisc GF filters feature a glass fiber prefilter over the membrane. This design ensures that even challenging samples can be filtered effectively without clogging, preserving the integrity of the filtration process. Pall's Glass Fiber (GF) Acrodiscs can also be used as standalone prefilters or in series with other Acrodiscs, offering flexibility for labs dealing with heavily particulate-laden samples.

In addition to these offerings, Pall's Acrodisc PVDF (LC) filters are hydrophilic polyvinylidene fluoride (PVDF) membranes suited for both aqueous and organic solvents, while the Acrodisc PTFE (CR) filters feature hydrophobic polytetrafluoroethylene (PTFE) membranes, which are ideal for non-aqueous solvents and highly acidic or basic samples. For ion chromatography applications, Supor PES (IC) Filters are available, providing certified low ionic backgrounds to ensure the accuracy of ion chromatography results.

With this broad range of membrane choices and formats, these filters help labs maintain peak performance and minimize the risk of contamination, downtime, and instrument damage.

FAQs About Waters Laboratory Filters

1. What types of laboratory filters does Waters offer?
Waters offers a wide range of laboratory filters, including syringe filters, membrane filters, and glass fiber filters.

2. What are the pore sizes available for Waters laboratory filters?
Waters laboratory filters are available in a variety of pore sizes, ranging from 0.2 µm to 5 µm.

3. Can Waters laboratory filters be used for both aqueous and organic solutions?
Yes, Waters laboratory filters are designed to be compatible with both aqueous and organic solutions.

4. Are Waters laboratory filters sterile?
Yes, some Waters laboratory filters are sterile and are designed for use in sterile applications.

5. What is the maximum operating temperature for Waters laboratory filters?
The maximum operating temperature for Waters laboratory filters varies depending on the specific filter type, but ranges from 40°C to 130°C.