When migrating your methods from HPLC to UPLC, remember these simple steps to success:

• Adjust column particle size and length to keep the L/dp constant

• Correctly scale flow rate for new column geometry, particle size, and separation duration

• With the ACQUITY UPLC Calculator, quickly and automatically transfer, scale, and optimize

Here’s where you are…

HPLC chart

Here’s where you could be…

UPLC chart

Achieve your best chromatography yet with ACQUITY UPLC – it’s easy to do!

The ACQUITY UPLC® System is designed to exploit the performance and efficiency of sub-2 µm column technology, without compromising your ability to run HPLC-scale separations with ease. Combine this with several column management options for both UPLC® and HPLC, and a range of column chemistries, and you’ll have the ability to work with a wide range of linear velocities, flow rates, and backpressures to suit the task at hand.

Take a Look at UPLC in Your Lab

You've seen what ACQUITY UPLC has done for science and business. Are you ready to see what it will do for you?

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