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Since 2003, Waters has developed innovative stationary phases for Hydrophilic Interaction Chromatography [HILIC] to overcome the challenge of retaining and separating extremely polar compounds. In addition to enhanced retention of polar compounds, ACQUITY UPLC® BEH, XBridge™ and Atlantis® HILIC columns provide increased mass spectrometry response, direct compatibility with sample preparation eluates [PPT, LLE and SPE] as well as orthogonal selectivity compared to RP materials, making HILIC an attractive alternative separation technique. Click below to explore the benefits of Waters HILIC columns. |
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