Nova-Pak Columns

Nova-Pak Columns

Scale-up from analytical to prep, simplified

Scale-up from analytical to prep, simplified

Reducing solvent consumption while maintaining resolution for complex mixtures is important, but that’s a challenge with larger particle sizes. With the smaller particle sizes and shorter column lengths in Nova-Pak Columns, those problems are a thing of the past. The bonded phases of Nova-Pak Columns are available in 4 µm and 6 µm particle sizes, offering high resolution and faster, more efficient chromatography over columns packed with larger particle sizes.

Nova-Pak Analytical Columns with 4 µm particle size packing offer a range of length options with 75, 100, 150, and 300 mm length steel columns. The semi-preparative Prep Nova-Pak HR Columns are packed with 6 µm particle size packings for unparalleled separation possibilities. The high-efficiency packing of Prep Nova-Pak HR Columns provides faster separations with less solvent for the added advantage of more concentrated fractions—reducing your preparative chromatography cost. To ensure batch-to-batch reproducibility, all Nova-Pak C18, C8, Cyano and Phenyl Columns are packed according to stringent quality control (QC) procedures in Waters cGMP manufacturing facility.

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Specifications

Overview

  • Reduces solvent consumption while maintaining resolution for complex mixtures
  • Packed to stringent QC procedures to ensure batch-to-batch reproducibility
  • Chemistries include C18, C8, Cyano, and Phenyl stationary phases
  • Available in 4 μm analytical and 6 μm semi-preparative particle sizes

Recommended Use: For higher resolution and faster chromatography.

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Stay compliant with smart column options

Ideal for compliant laboratories, a smart column option is available for identifying and tracking column information. The eConnect column tag is a permanently attached electronic tag device for HPLC columns used with Alliance iS HPLC System that is optional. Data from this device can be accessed using the system’s console. This smart tag device provides a quick overview of column history and can be utilized as a basic troubleshooting tool. Data residing on the device is automatically imported by and later searchable via Empower CDS. 

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Nova-Pak Columns

The Waters Nova-Pak Columns are a cornerstone in high-performance liquid chromatography (HPLC), known for their versatility, reliability, and exceptional performance across a broad range of applications. These columns are a popular choice among researchers and analysts, offering a perfect balance of high efficiency and durability that make them an indispensable tool in laboratories worldwide.

The Nova-Pak Columns are engineered with particle sizes of 4 µm for analytical applications and 6 µm for semi-preparative tasks, enhancing resolution and reducing analysis time compared to columns with larger particle sizes. The high-efficiency packing ensures that even complex mixtures can be separated with precision, maintaining the integrity of the analysis while also reducing solvent consumption. This combination of superior resolution and efficiency makes Nova-Pak Columns particularly valuable in environments where time and resource management are critical.

These columns are available with a variety of bonded phases, including C18, C8, Cyano, and Phenyl, providing optimal selectivity for different types of separations. This versatility allows Nova-Pak Columns to be used in a wide range of fields, from pharmaceuticals to environmental analysis, food and beverage testing, and beyond. Whether you are working on the separation of small molecules like peptides and proteins, analyzing pharmaceuticals for active ingredients and impurities, monitoring environmental contaminants such as pesticides and herbicides, or conducting food and beverage quality control, Nova-Pak Columns deliver consistent and reliable results.

One of the key strengths of Nova-Pak Columns is their durability. These columns are designed to withstand high pressures, making them suitable for the most demanding HPLC applications. The robust construction ensures that they can endure repeated use without compromising on performance, which is crucial for maintaining consistent results across multiple analyses.

Waters Corporation has maintained stringent quality control standards in the manufacturing of Nova-Pak Columns, ensuring batch-to-batch reproducibility. This level of quality assurance means that you can trust these columns to deliver reliable and reproducible results every time. The columns are available in various formats, including analytical columns for routine analysis and method development, preparative columns for larger-scale purification, and Radial-Pak columns designed for high-throughput analysis and screening. This range of options allows researchers to choose the most appropriate column for their specific needs, enhancing the flexibility and applicability of the Nova-Pak line.

For compliant laboratories, Nova-Pak Columns even offer a smart column option. The eConnect column tag, a permanently attached electronic device, provides comprehensive column information and history, streamlining data access and troubleshooting. Compatible with the Alliance iS HPLC System, this smart tag allows for easy integration of column data into Empower CDS, aiding in compliance and operational efficiency.

Nova-Pak Columns offer a reliable and versatile solution for a wide range of HPLC applications. Their high efficiency, durability, and broad application range make them a popular choice among researchers and analysts across various industries. Whether you are looking to optimize selectivity in different separations, reduce solvent consumption, or ensure reproducibility in your analyses, Nova-Pak Columns provide the performance and reliability you need to achieve superior results.

FAQs About Waters Nova-Pak Columns

1. What is the composition of Waters Nova-Pak Columns?
Waters Nova-Pak Columns are made of silica-based stationary phases that are bonded with hydrophobic ligands.

2. What is the recommended pH range for using Waters Nova-Pak Columns?
Waters Nova-Pak Columns are recommended for use in the pH range of 2-8.

3. What is the maximum operating pressure for Waters Nova-Pak Columns?
The maximum operating pressure for Waters Nova-Pak Columns is 4000 psi.

4. What is the recommended temperature range for using Waters Nova-Pak Columns?
Waters Nova-Pak Columns are recommended for use in the temperature range of 10-40°C.

5. What applications are Waters Nova-Pak Columns suitable for?
Waters Nova-Pak Columns are suitable for a wide range of applications, including the separation of small molecules, peptides, and proteins. They are commonly used in pharmaceutical, biotech, and food and beverage industries.