Sugar Substitute Testing

Sugar Substitute Testing

Standardized, reliable workflows for analyzing sugar substitutes are critically important to food and beverage production and raw material testing. Waters are committed to supporting you in overcoming your analytical challenges, ensuring product quality, and safeguarding your brand reputation.

Standardized, reliable workflows for analyzing sugar substitutes are critically important to food and beverage production and raw material testing. Waters are committed to supporting you in overcoming your analytical challenges, ensuring product quality, and safeguarding your brand reputation.

Sports drinks in ice tub
Sports drinks in ice tub

Overview

As the demand for healthier food options grows, so does the need for accurate and consistent sugar substitute analysis. At Waters, we recognize the complex challenges faced by manufacturers, ingredient suppliers, and testing laboratories in this dynamic landscape. From identifying the right sweeteners to ensuring adherence to regulatory compliance, our expertise empowers you to effectively navigate the complexities of sugar substitutes.

Discover Waters solutions for reliable analysis of both artificial and novel sweeteners, including saccharin, aspartame, and steviol glycosides. Our commitment extends beyond ensuring accurate sugar analysis in food and beverages; our quality solutions also help testing laboratories to maintain standardization and consistency across different manufacturing facilities.


Applications

We understand the critical importance of fast and precise analysis of the content and ratios of common additives in soft drink production. Our comprehensive and user-friendly solutions help not only to ensure safety and reliability of your products but also to improve overall quality control of the production process.

We understand the critical importance of fast and precise analysis of the content and ratios of common additives in soft drink production. Our comprehensive and user-friendly solutions help not only to ensure safety and reliability of your products but also to improve overall quality control of the production process.


The chemical structure of artificial sweeteners and the complex nature of food matrices could pose challenges to their analysis. Explore how each sweetener type uniquely benefits from the innovative technologies offered by Waters.

The chemical structure of artificial sweeteners and the complex nature of food matrices could pose challenges to their analysis. Explore how each sweetener type uniquely benefits from the innovative technologies offered by Waters.


Ensuring the purity of natural sweeteners is crucial for the safety of final products. Novel sweeteners derived from natural sources exhibit greater complexity in their chemical structure, which can create analytical challenges. Waters solutions minimize the ambiguity in your analyses and enhance confidence in product safety and quality.

Ensuring the purity of natural sweeteners is crucial for the safety of final products. Novel sweeteners derived from natural sources exhibit greater complexity in their chemical structure, which can create analytical challenges. Waters solutions minimize the ambiguity in your analyses and enhance confidence in product safety and quality.




Case Study: Ensuring Compositional Accuracy During Soft Drink Manufacturing

The Coca-Cola Bottling Company UNITED (CCBCU) QC laboratories are responsible for verifying the composition of in-process products, ensuring the “big 6” additives, including sugar substitutes acesulfame K, aspartame, and saccharin, are present in the specified concentrations. Read this case study to learn why Coca-Cola decided the ACQUITY UPLC H-Class System and Waters Beverage Analysis Kit matched their needs.

The Coca-Cola Bottling Company UNITED (CCBCU) QC laboratories are responsible for verifying the composition of in-process products, ensuring the “big 6” additives, including sugar substitutes acesulfame K, aspartame, and saccharin, are present in the specified concentrations. Read this case study to learn why Coca-Cola decided the ACQUITY UPLC H-Class System and Waters Beverage Analysis Kit matched their needs.


Rows of soda or beer cans

Solutions


With Waters systems, characterize sugar substitutes in food and beverage product samples in less time and with greater confidence.

With Waters systems, characterize sugar substitutes in food and beverage product samples in less time and with greater confidence.

Highly reliable, low complexity, accurate routine analysis

Highly reliable, low complexity, accurate routine analysis

Rely on the Arc HPLC System for first time accurate results, high-efficiency separations, and quality data to meet your regulatory requirements with confidence.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

A new era of intuitive simplicity

A new era of intuitive simplicity

Reduce human errors, HPLC system downtime, and generate consistent global method performance with the Alliance iS HPLC System to maximize the productivity and efficiency of your QC lab.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Performance that drives productivity

Performance that drives productivity

Improve the characterization of your most complex samples and decrease your time to result with the ACQUITY UPLC H-Class PLUS System.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

See clearly and consistently, with confidence

See clearly and consistently, with confidence

Reduce non-specific adsorption from metal interactions in HPLC and UHPLC applications to get a full picture of your sample with the Arc Premier System.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Separate beyond question with the power of mass detection

Separate beyond question with the power of mass detection

Complementary to optical detection, the ACQUITY QDa II Mass Detector works in harmony with your chromatography to minimize the risk of unexpected components or co-elutions, and confirm trace sample constituents with confidence in a single workflow with single quadrupole mass detection.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Reliable, repeatable analysis of non-absorbing components

Reliable, repeatable analysis of non-absorbing components

Designed to provide scientists with the highest sensitivity, stability, and reproducibility, the 2414 Refractive Index (RI) Detector is the ideal solution for the analysis and quantification of components with limited or no UV absorption, such as alcohols, sugars, saccharides, fatty acids, and polymers.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Putting confidence in your detection strategy

Putting confidence in your detection strategy

The Waters 2424 Evaporative Light Scattering (ELS) Detector, with its compact and innovative design, offers near universal detection of non-volatile and semi-volatile sample components.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Waters software streamlines data acquisition, processing, and reporting of sugar substitute test results.

Waters software streamlines data acquisition, processing, and reporting of sugar substitute test results.

Elevate your chromatography with the universal language of the lab

Elevate your chromatography with the universal language of the lab

Simplify the way you collect, manage, and report chromatography test results with Empower CDS. Empower CDS helps your entire laboratory operate more efficiently and securely with the industry's most advanced data acquisition, management, processing, analytics, and reporting capabilities.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Support the entire product lifecycle from discovery to manufacturing

Support the entire product lifecycle from discovery to manufacturing

NuGenesis Software seamlessly links data from the lab to the business operations of the enterprise with functionality such as sample submission and results review, stability testing, scientific search, multi-vendor software connection, laboratory inventories, data retention and legal hold, and laboratory execution methods.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Our reliable and robust columns and consumables can be easily integrated into your sugar substitute testing workflows.

Our reliable and robust columns and consumables can be easily integrated into your sugar substitute testing workflows.

A simplified solution for quantitating soft drink additives

A simplified solution for quantitating soft drink additives

Implement Waters simple but comprehensive HPLC Beverage Analysis Kit for the rapid quantitation of 6 common additives (acesulfame-K, saccharin, caffeine, benzoate, sorbate, and aspartame).

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Designed, tested, and guaranteed for routine use

Designed, tested, and guaranteed for routine use

Dramatically increase resolution, speed, and sensitivity with Waters Ultra-Performance Liquid Chromatography (UPLC) columns, designed for superior pH stability, maximum retentivity, improved peak shape, and ultimate efficiency.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Create exceptional chromatography and achieve repeatable results

Create exceptional chromatography and achieve repeatable results

Resolve your toughest separation challenges with Waters analytical and preparative HPLC columns, which come in 5,800+ column formats, 175+ column configurations, and 21 unique column phases — for excellent column-to-column reproducibility.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Faster, cleaner, and simpler sample preparation starts here

Faster, cleaner, and simpler sample preparation starts here

Simplify sample preparation with Waters sample preparation solutions for quantitative analysis and deliver samples that are reproducible, yield high recovery, and are free of interferences.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Control, certainty & compliance: maximize lab efficiency with Certified Vials

Control, certainty & compliance: maximize lab efficiency with Certified Vials

Chemical cleanliness testing and other, multi-step certification test procedures ensure that your sample vials perform reliably vial-to-vial, so you can have certainty in you results.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

The right lab filter for any sample type

The right lab filter for any sample type

With Pall Life Sciences Filters from Waters, you can confidently meet your regulatory and quality objectives. The filters that have been designed, developed, and certified for compliance.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Achieve accurate results for several forensic screening, confirmation, and quantitation workflows using streamlined Waters analytical services.

Achieve accurate results for several forensic screening, confirmation, and quantitation workflows using streamlined Waters analytical services.

Your success is just a click away

Your success is just a click away

Optimize your laboratory's productivity while addressing your budget realities with Waters Global Services. Maintain peak system performance, minimize down time, address scientific application challenges, and support stringent compliance requirements.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

Make science more accessible with Waters Capital

Make science more accessible with Waters Capital

Maximize your lab resources and minimize risk with payment options from Waters Capital, which includes innovative solutions to upgrade aging instruments, customized support, and flexible options to bundle your complete laboratory solution in one easy monthly payment – everything you need to advance your science.

  • Soft Drink Analysis
  • Artificial Sweeteners
  • Natural Sweeteners

The data speaks for itself

The data speaks for itself
Optimized separation of soft drink additives with aspartame degradants on an Arc HPLC System.
Comparison of separation efficiency of steviol glycosides obtained on XSelect Premier HSS T3 Column and on XSelect HSS T3 Column under the same experimental conditions.
Separation of sugar alcohol and allulose (5 mg/mL) using the Atlantis Premier BEH Z-HILIC Column on an Arc HPLC System.
Comparable chromatographic performance in beverage standard analysis using ACQUITY UPLC H-Class PLUS System and ACQUITY UPLC H-Class System.

Webinars and Resources



  • eBook

Your Essential Guide to Sugar Analysis with Liquid Chromatography

Your Essential Guide to Sugar Analysis with Liquid Chromatography
  • eBook

Selecting a Liquid Chromatography Solution for Testing Sugars and Sweeteners in Beverages

Selecting a Liquid Chromatography Solution for Testing Sugars and Sweeteners in Beverages
  • Application Notebook

Food and Beverage Quality Control and Compositional Testing

Food and Beverage Quality Control and Compositional Testing
  • Case Study

Liquid Handling Automation System Streamlines Sample Preparation for Nutritional Analysis

Liquid Handling Automation System Streamlines Sample Preparation for Nutritional Analysis


Learn more about Sugar Substitute Testing.

Learn more about Sugar Substitute Testing.

Sports drinks in ice tub
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