• Application Note

Cyclizine and Chlorcyclizine

Cyclizine and Chlorcyclizine

  • Waters Corporation

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief details on analysis of cyclizine and chlorcyclizine using Symmetry Columns. 

Introduction

The compounds analyzed in this study are: 

  1. Cyclizine  
  2. Chlorcyclizine HCL 

Experimental

HPLC Method

Column:

Symmetry C8, 3.9 x 150 mm, 5 µm

Guard column:

Symmetry Guard Column 3.9 x 20 mm, 5 µm

Part numbers:

Column - WAT046970, Guard - WAT054250

Mobile phase:

7.4 mM sodium 1-heptanesulfonate in water/acetonitrile 65:35

Flow rate:

1.0 mL/min

Injection volume:

8 µL of 100 µg/mL sample

Detection:

UV @ 230 nm

USP Tailing Factors

  1. 1.28
  2. 1.28 

Results and Discussion

Featured Products

WA31763.65, June 2003

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