Waters Fraction Collector III

The Waters Fraction Collector III is an adaptable and reliable tool for collecting purified material from your liquid chromatography (LC) systems. Designed for both high performance liquid chromatography (HPLC) and LC-MS applications, this easy-to-use fraction collector enhances laboratory workflows by allowing for the efficient and precise collection of fractions in a user-friendly, cost-effective manner.

The Fraction Collector III is capable of handling flow rates as high as 300 mL per minute, making it suitable for a broad range of laboratory scales and requirements. Its versatile design supports various adapter racks and collection vessels, from microtiter plates to multiple container setups.

Operation of the Fraction Collector III is straightforward thanks to its intuitive keypad and view screen, which simplify setup and make it accessible even for users with limited technical expertise. The device allows for real-time results review as well as access to a post-run results table, ensuring that users can easily monitor and adjust their collection protocols as needed.

Compatible with the LC Prep 150 System, LC Prep AutoPurification System, and Modular Systems, the Fraction Collector III integrates seamlessly into existing workflows. It also offers remote management capabilities through MassLynx Software, which is particularly useful for mass spectrometry (MS) applications, enhancing its utility in more complex analytical environments.

The Fraction Collector III features several modes of collection to accommodate various laboratory needs, including time-based, threshold-based, volume-based, manual, and sampling modes. These can be combined for advanced collection strategies, such as pooling of repeated runs into common vessels, thereby optimizing productivity and efficiency in preparative LC applications.

One of the standout features of the Fraction Collector III is its peak detection and collection capability, which utilizes an analog detector input from an LC system for fully automated collection of peaks of interest. The system's diverter valve is strategically designed to collect peaks while diverting extraneous solvent and unwanted peaks to waste, maximizing the efficiency of fraction collection and overall preparative LC system productivity.

For maximum control and usability, the Fraction Collector III can be operated directly from a local keypad or remotely through serial port communication by Empower 3 or MassLynx Software. This dual functionality provides flexibility in how the device is controlled, catering to both standalone and integrated system setups.

The integrated instrument control software interface further enhances the usability of the Fraction Collector III. It allows users to configure collection vessels, program collection routines, and receive real-time feedback on the state of the collection process and the location of collected fractions. For labs requiring specific setups, multiple collector rack configurations, including custom configurations, are available to accommodate a variety of collection vessels. Additionally, the interface's override function permits manual collection directly from the instrument control panel, offering an extra layer of control when needed. The Waters Fraction Collector III is an essential tool for laboratories engaged in HPLC and LC-MS applications, providing a robust, flexible solution for the collection of a variety of fraction sizes and enhancing overall laboratory efficiency and productivity.