Alliance iS HPLC System

Alliance iS HPLC System

A new era of intuitive simplicity

A new era of intuitive simplicity

Quality Control (QC) labs face stringent, ever-evolving compliance and data quality requirements to release products within tighter timelines and budgets. These problems become exaggerated due to staff turnover and training requirements.

To address these problems, the Alliance iS HPLC System elevates your QC lab with first-time right results, shortened release cycles, and fewer investigations by:

  • Reducing human errors by up to 40%* through innovative system intelligence that addresses errors before they can occur
  • Enhancing productivity and asset management with safeguards to ensure correct system performance
  • Maximizing system uptime and minimizing service intervention

*based on Waters’ market research in 2022, surveying 56 global Pharma QC labs running >25 systems.

Alliance iS HPLC System identifies potential user and system errors earlier, reducing the number of retests and investigations. Alliance iS HPLC System

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Alliance iS HPLC System Savings Calculator

Your lab ally knows your needs

Your lab ally knows your needs

Use our savings calculator to discover how much time and money you could save with the Alliance iS HPLC System, the intuitively simple HPLC system designed to reduce common errors, enhance efficiency, and increase uptime.

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Specifications

Maximum operating pressure

12,000 psi

pH range

1 to 13

Operating flow rate range

0.001 to 10.000 mL/min

Injection type

Flow-through needle

Sample flow path

Stainless steel

Sample carryover

≤0.002% [Caffeine] under UV conditions

Sample compartment

4 to 40 °C

Pump options

Quaternary

Solvent conditioning

Passive pre-heating

Column tracking

Yes, with RFID enabled eConnect Waters Columns

Column capacity

1 column up to 300 mm length, up to 8 mm internal diameter (I.D)

Maximum sample capacity

(any three of the following)

48-position, 2.00-mL vial holder

54-position, 2.00-mL vial holder

96-well plate

384-well plate

48-position, 0.65-mL micro-centrifuge tube plate

24-position, 1.50-mL micro-centrifuge plate

Detector options

PDA Detector, TUV Detector

Informatics compatibility

Empower Chromatography Data System (CDS)

(Feature Release 4 with Windows 10 and later)

Physical Specifications

Height: 74.2 cm (29.23 in.)

Width: 49.9 cm (19.64 in.)

Depth: 63.5 cm (24.99 in.)

Weight: 72.5 kg (160.0 lbs.)

Overview

  • Multiply the productivity and efficiency of your QC lab by reducing human error with hardware and intuitive touchscreen tools that stop unacceptable runs before they can occur
  • Secure your data integrity and consistency and maximize system uptime through consistent user operations with guided operational tools that ensure proper system preparation
  • Amplify your lab’s return on investment (ROI) on equipment and analysts through enhanced situational awareness and automated system health monitoring that quickly communicates system status and streamlines decision making
  • Reduce unexpected system downtime and shorten the break-fix cycle with guided troubleshooting and maintenance and enhanced component serviceability, all available on the instrument touchscreen
  • Count on repeatable global method performance with improved thermal stability, hardware compatibility with legacy methods, and intelligent method translator tools
  • Reduce carryover and improve temperature stability with the latest in Waters historically dependable instrument technology
  • Learn more about how easy the Alliance iS HPLC System is to use with our series of how-to videos

Recommended Use: For QC labs with a drive to reduce human errors and unexpected downtime.

Features Header

Features Header

Meet your new lab ally

Mistakes in the lab come in many forms: forgotten samples, incorrect solvent levels, incorrect tightening of system fittings, or not verifying correct system performance. Regardless, mistakes lead to repeated procedures and possibly time-consuming investigations.

Built for Empower Software, the Alliance iS HPLC System coupled with Empower CDS and Empower LMS serves as your assistant – preventing common errors with pre-run verification of the correct column, vials, and plates, as well as solvent levels and expiration dates.

Additionally, the Alliance iS HPLC System’s tool-free fittings, clearly labeled and organized solvent lines, and auto-recognition of Waters eConnect HPLC Columns prevent leaks and user errors when setting up the system for analysis. Integrated hardware components standardize your fleet to ensure proper system configurations for your analysis.

Enjoy stress-free analysis

Employee turnover makes training a continual challenge and can lead to inconsistencies and decreased productivity. The Alliance iS HPLC System keeps you and your lab stress-free and running smoothly with an intuitive touchscreen that supports learning the system and producing consistent, quality results.

The instrument touchscreen interface provides at-instrument guided workflows for system start-up, shutdown, and priming – helping to ensure all your users are preparing their systems sufficiently and identically.

Intuitively simple for informed decisions

Managers and analysts need to make quick decisions. Ambiguous system performance status impedes the ability to select, maintain, and service instruments.

The Alliance iS HPLC System is designed with intuitive system mechanisms to give fast feedback that your team can act upon to get the best return on investment of your equipment. Using the combination of status lights on the system, the touchscreen interface, Empower Software, and integration with waters_connect System Monitoring, your team can immediately understand your system operation. Additionally, your lab can leverage health monitoring tools to dive deeper into the crucial performance parameters of your system. 

Maximize system uptime with help at your fingertips

Nothing disrupts operations like unexpected system downtime. The Alliance iS HPLC System is built upon Waters strong legacy of reliable instrument performance while also improving upon previous generations. Improvements to our injector, mixer, column manager, check valves, and detectors maximize the reliability of your instrument.

The touchscreen interface also provides guided troubleshooting and guided maintenance, and the system has been optimized to provide easy access to serviceable components. The touchscreen interface also enables easy access to the Waters service department with quick and easy access to the Waters Help Center.

With the Alliance iS HPLC System, you can ensure your system will be more reliable than ever while minimizing unscheduled downtime should anything unexpected occur.

Support your compliant, global business network

Your systems need to support both legacy and new methods that can be operated repeatably anywhere in the world while meeting regulatory requirements. These requirements can also place a large burden on your analysts, but failing to perform necessary tasks could put your organization at risk.

The Alliance iS HPLC System features improved enhanced temperature control in the sample manager, column manager, and detector to match global needs. Additionally, when coupled with Empower Software Solutions and eConnect HPLC Columns, analysts gain access to new features:

  • Intelligent Method Translator App (iMTA) to assist with method migration from other systems
  • Method Matching warns users when attempting to use an unsupported method on the system
  • Empower System Audit Trail automatically captures installation of and modifications to the system and system software for added traceability
  • Automated column history tracking

Resources

Documents

Documents

Explore documents, videos, and other resources to support your Waters solution.

Explore All Alliance iS HPLC System Support

Videos

Videos
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Related

Alliance HPLC System
Providing versatile, dependable performance for analytical labs, the Alliance HPLC family meets the rigorous requirements of routine chromatography and the performance standards of new-product research and method development.

Empower Chromatography Data System (CDS)
For advanced laboratory data management, including acquisition, processing and reporting for liquid and gas chromatography instruments, equip your lab with the Empower Chromatography Data System (CDS).

waters_connect System Monitoring
Maximize productivity and effectively utilize resources with real-time lab management provided by waters_connect System Monitoring software.

eConnect Column Tag Technology
Identify HPLC column performance and create column usage logs with the eConnect Column Tag Technology, the only fully automated solution to help in replacement decisions and root-cause batch investigations.
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Alliance iS HPLC System: Empowering Analytical Excellence

The "Alliance iS HPLC System," crafted by the esteemed analytical instruments and solutions manufacturer, Waters Corporation, stands as a specialized high-performance liquid chromatography (HPLC) system. Its core mission is to cater to the specific requirements of analytical and research settings, notably in laboratory and scientific environments.

The principal objective of the Alliance iS HPLC System centers around delivering consistent and reliable chromatographic separation, an essential technique for dissecting intricate mixtures into their constituent parts. The system is meticulously designed to ensure the precision, uniformity, and trustworthiness of this separation process.

To achieve this, the Alliance iS HPLC System integrates an array of features and innovations aimed at enhancing its overall performance. Notably, it excels in minimizing potential errors, a pivotal concern as inaccuracies can compromise result precision and system dependability. The system's design and software are likely equipped with protective measures and automation to mitigate the possibility of human error throughout the phases of sample preparation and analysis.

Furthermore, the system is finely tuned to optimize its general performance, emphasizing efficient operation with attributes that expedite analysis and ensure steadfast, reproducible results. Researchers and analysts can rely on its capacity to yield top-quality data consistently.

In summary, the "Alliance iS HPLC System" from Waters Corporation is a specialized HPLC system meticulously tailored for applications in analytical and research domains. Its central mission is to furnish consistent and dependable chromatographic separation, featuring elements that mitigate human errors and enhance overall system efficiency, rendering it an invaluable tool across a broad spectrum of scientific pursuits.

Enhancing Research with the Alliance iS HPLC System

In response to the evolving demands of Quality Control (QC) labs, the Alliance iS HPLC System introduces a new era of intuitive simplicity. These labs are continually pressured to meet strict compliance and data quality standards while managing tighter timelines and budgets, often exacerbated by staff turnover and training needs. The Alliance iS system addresses these challenges by delivering first-time accurate results, shortening product release cycles, and reducing the need for investigations. It accomplishes this by proactively reducing human errors by up to 40%, enhancing productivity and asset management, and maximizing system uptime, all while minimizing service intervention.

Alliance iS HPLC System FAQs

1.How does the Alliance iS HPLC System differ from the Alliance HPLC System?
The Alliance iS HPLC System builds upon the foundation of the Alliance HPLC System, with several key enhancements like improved automation, allowing for more streamlined workflows and reduced manual intervention. The iS system also features advanced data management tools that enhance data integrity and compliance with regulatory standards.
Additionally, this version provides greater flexibility with enhanced compatibility options for various detectors and software. These upgrades make the Alliance iS system more efficient and user-friendly, particularly in environments where high throughput and stringent data management are essential.

2.What are the benefits of using the Alliance iS HPLC System for pharmaceutical analysis?
The Alliance iS HPLC System offers significant benefits for pharmaceutical analysis, including high precision and reproducibility, which are critical for drug testing and quality control. The system's advanced automation reduces the potential for human error, ensuring more consistent results. Its improved data management features support compliance with regulatory requirements, such as 21 CFR Part 11, which is crucial in pharmaceutical research and manufacturing.
Moreover, the system's flexibility allows it to handle a wide range of applications, from stability studies to impurity profiling, making it an ideal choice for pharmaceutical labs.

3. What are the system's compatibility options with other laboratory instruments and software?
The Alliance iS HPLC System is designed with compatibility in mind, allowing seamless integration with various laboratory instruments and software platforms. It is compatible with Waters Empower Software, which offers robust data acquisition, processing, and reporting capabilities. The system can also interface with multiple detectors, such as PDA, UV, and MS, providing flexibility in method development and analysis.
The Alliance iS system supports connectivity with laboratory information management systems (LIMS), enhancing data flow and overall lab efficiency. This level of compatibility ensures that the system can be easily integrated into your existing laboratory workflows.