HPLC Systems

HPLC Systems

Ideal for users of all experience levels, Waters Dependability line of high-performance liquid chromatography (HPLC) systems are synonymous with cost-effective, highly reliable results for your everyday applications—without sacrificing data quality. 

Ideal for users of all experience levels, Waters Dependability line of high-performance liquid chromatography (HPLC) systems are synonymous with cost-effective, highly reliable results for your everyday applications—without sacrificing data quality. 
ACQUITY Premier System BSM FTN CH-A Xevo TQ-XS UniSpray Tray Bottles Angled

With Waters trusted line of Dependability solutions, you can achieve highly efficient and reliable HPLC separations with peace of mind and ease; obtain the industry-leading, compliance-ready feature sets for data that is accurate, trustworthy, and reliable; minimize variability and facilitate reliable method transfer; and easily upgrade as your lab expands. 


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  • Alliance iS HPLC System
    Alliance iS HPLC System

    Reduce human errors, HPLC system downtime, enhance productivity and generate consistent method performance anywhere with the Alliance iS High Performance Liquid Chromatography (HPLC) System.

  • Alliance iS Bio HPLC System
    Alliance iS Bio HPLC System

    Minimize unwanted analyte-surface interactions, reduce common errors, and achieve faster, more reliable results in biopharma applications with the Alliance iS Bio HPLC System.

  • Alliance HPLC System
    Alliance HPLC System

    Confidently generate data that’s regulatory compliant with the Alliance HPLC System, ideal for HPLC methods development and routine LC analysis.

  • Analytical Scale Purification System
    Analytical Scale Purification System

    Enjoy high-capacity sample processing and fraction collection at smaller preparative chromatography scales with a more efficient and cost-effective purification solution, the Analytical-Scale Purification System.

  • Arc HPLC System
    Arc HPLC System

    Count on the Waters Arc HPLC System for high-efficiency LC separations and quality data that meet your regulatory requirements with confidence.

  • Breeze QS HPLC
    Breeze QS HPLC

    For routine HPLC analysis with a choice of multiple components and simple-to-use software, the Breeze QS HPLC System delivers world-class performance – affordably.

  • Modular Systems
    Modular Systems

    Simplify your analytical to semi-preparative chromatography purification workflow and purify your compounds easier with Waters Modular Systems.

HPLC Systems

Waters HPLC Systems are designed to meet the diverse and demanding needs of modern analytical laboratories, with unparalleled performance, reliability, and versatility. These systems provide the precision and efficiency required for a wide range of applications, from routine analysis to complex research projects.

At the heart of Waters HPLC Systems is a commitment to delivering accurate and reproducible results. The systems are engineered with advanced technology that ensures high resolution, sensitivity, and speed. Whether you are performing quantitative analysis, method development, or quality control, Waters HPLC Systems deliver consistent and reliable data, making them an essential tool for any laboratory.

One of the key advantages of Waters HPLC Systems is their flexibility. These systems are designed to accommodate a variety of column chemistries and mobile phases, allowing users to tailor their methods to specific analytical needs. This versatility is particularly important in research and development settings, where the ability to adapt and optimize methods can significantly impact the quality and efficiency of the work.

Waters HPLC Systems are equipped with state-of-the-art detectors that provide precise and sensitive measurements. The range of available detectors, including UV/Vis, PDA, fluorescence, and mass spectrometry, ensures that users can select the most appropriate detection method for their specific application.

With intuitive software interfaces, such as Empower Chromatography Data System, these HPLC systems simplify the process of method development, data acquisition, and analysis. These systems are designed to minimize the learning curve for new users while providing advanced features for experienced operators.

Waters HPLC Systems are built for durability and long-term reliability. The robust construction and high-quality components ensure that the systems can withstand the rigors of daily use in busy laboratories. Regular maintenance and support are simplified by the availability of Waters' comprehensive service programs, which help to maximize system uptime and performance. This commitment to reliability and support underscores Waters' dedication to customer satisfaction and long-term partnership.

Waters invests heavily in research and development to ensure that their systems remain at the cutting edge of chromatography technology. Recent advancements include improvements in system automation, increased throughput capabilities, and enhanced environmental sustainability features. These innovations not only improve the performance of the systems but also align with the evolving needs of the scientific community.

HPLC Systems from Waters offer a combination of performance, reliability, and versatility that makes them an indispensable tool for modern analytical laboratories. Their advanced technology, flexible design, and ease of use ensure that they can meet the needs of a wide range of applications. Supported by Waters' legacy of innovation and customer service, these systems provide the accuracy, efficiency, and dependability that scientists require to achieve their analytical goals.

HPLC Systems

1.What types of applications are Waters HPLC Systems suitable for?
Waters HPLC Systems are versatile and suitable for a wide range of applications, including pharmaceutical research and development, quality control, environmental analysis, food and beverage testing, and academic research. Their flexibility and advanced technology make them ideal for both routine analysis and complex research projects.

2.What detectors are available for Waters HPLC Systems?
Waters offers a variety of detectors for their HPLC Systems, including UV/Vis, Photodiode Array (PDA), fluorescence, and mass spectrometry detectors. This range allows users to select the most appropriate detection method for their specific application, enhancing the system's performance and utility.

3.What is a Modular HPLC System, and how does it differ from other HPLC systems?
A Modular HPLC System is composed of separate, interchangeable modules such as pumps, detectors, and sample managers. This modularity allows users to customize the system to their specific needs, making it highly versatile and adaptable for various applications.

4.What is the ACQUITY UPLC System?
The ACQUITY UPLC System (Ultra Performance Liquid Chromatography) offers higher resolution, sensitivity, and speed compared to traditional HPLC systems. It uses sub-2-micron particle columns, which allow for faster analysis times and better separation performance.