Chromatography Systems

Chromatography Systems

Meet all your application requirements with Waters chromatography systems, including our Dependability line of HPLC Systems, Flexibility line of HPLC/UHPLC Systems, Performance line of UHPLC/UPLC Systems, Purification Systems, and Specialty Systems.

Meet all your application requirements with Waters chromatography systems, including our Dependability line of HPLC Systems, Flexibility line of HPLC/UHPLC Systems, Performance line of UHPLC/UPLC Systems, Purification Systems, and Specialty Systems.
ACQUITY Premier System BSM FTN CH-A Xevo TQ-XS UniSpray Tray Bottles Angled

Data is paramount in scientific research as evidence-based questions escalate. Scientists across many industries rely on Waters liquid chromatography (LC) and liquid chromatography-mass spectrometry (LC-MS) platforms to identify and understand chemical components and answer their important questions. With Waters as your measurement partner, you’ll get the tailored chromatography solution you need to achieve your workflow and analysis requirements.

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HPLC Systems
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UHPLC/UPLC Systems
Purification Systems
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Showing 28 results
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  • Alliance iS HPLC System
    Alliance iS HPLC System

    Reduce human errors, HPLC system downtime, enhance productivity and generate consistent method performance anywhere with the Alliance iS High Performance Liquid Chromatography (HPLC) System.

  • Alliance iS Bio HPLC System
    Alliance iS Bio HPLC System

    Minimize unwanted analyte-surface interactions, reduce common errors, and achieve faster, more reliable results in biopharma applications with the Alliance iS Bio HPLC System.

  • Arc Premier System
    Arc Premier System

    Reduce non-specific adsorption from metal interactions in HPLC and UHPLC applications and obtain higher quality, reproducible data with the Arc Premier System.

  • ACQUITY Advanced Polymer Chromatography (APC) System
    ACQUITY Advanced Polymer Chromatography (APC) System

    Perform polymer and oligomer analysis faster with the ACQUITY Advanced Polymer Chromatography System, a breakthrough APC instrument for high-resolution polymer characterization.

  • ACQUITY Arc Multi-Dimensional Liquid Chromatography (MDLC) System
    ACQUITY Arc Multi-Dimensional Liquid Chromatography (MDLC) System

    Achieve highly repeatable and accurate multi-dimensional HPLC separations for complex samples with the ACQUITY Arc Multi-Dimensional Liquid Chromatography (MDLC) System.

  • ACQUITY Arc System
    ACQUITY Arc System

    Bridge the gap between HPLC and UHPLC applications while continuing to support validated assays with the ACQUITY Arc System, which offers the flexibility you need for HPLC and UHPLC workflows.

  • ACQUITY Premier System
    ACQUITY Premier System

    Minimize metal-sensitive analyte loss and improve recovery with the ACQUITY Premier System for ultra-performance liquid chromatography analysis.

  • ACQUITY Premier System with Multi-Dimensional Technology
    ACQUITY Premier System with Multi-Dimensional Technology

    Achieve maximum peak capacity and ensure accuracy and precision of the entire assay with the ACQUITY Premier System with Multi-Dimensional Technology.

  • ACQUITY UPC2 System
    ACQUITY UPC2 System

    Address routine and complex separation challenges while delivering the reliability, robustness, sensitivity, and increased throughput of convergence chromatography techniques with the ACQUITY UPC2 System.

  • ACQUITY UPLC H-Class PLUS System
    ACQUITY UPLC H-Class PLUS System

    Get the flexibility of quaternary or binary solvent blending with the advanced performance of UHPLC analysis with the ACQUITY UPLC H-Class PLUS System.

  • ACQUITY UPLC I-Class PLUS System
    ACQUITY UPLC I-Class PLUS System

    Improve your resolving power, lower your system volume and achieve the tallest, sharpest peaks with the ACQUITY UPLC I-Class PLUS System.

  • ACQUITY UPLC M-Class System
    ACQUITY UPLC M-Class System

    Achieve the sensitivity of micro- and nanoflow liquid chromatography with UPLC technology when you equip your lab with the ACQUITY UPLC M-Class System.

  • ACQUITY UPLC M-Class System with 2D Technology
    ACQUITY UPLC M-Class System with 2D Technology

    Achieve more sensitive LC-MS analyses and reliable, high-performing nano- to microscale two-dimensional UPLC (UHPLC) separations with the ACQUITY UPLC M-Class System with 2D Technology.

  • ACQUITY UPLC M-Class System with HDX Technology
    ACQUITY UPLC M-Class System with HDX Technology

    Leverage UPLC separations and high-resolution mass spectrometry (HRMS) to confidently identify changes in protein conformation with the ACQUITY UPLC M-Class System with HDX Technology.

  • ACQUITY UPLC Systems with 2D LC Technology
    ACQUITY UPLC Systems with 2D LC Technology

    Ensure accuracy and precision for complex samples with the lowest dispersion two-dimensional chromatography system for maximum peak capacity, the ACQUITY UPLC Systems with 2D LC Technology.

  • Alliance HPLC System
    Alliance HPLC System

    Confidently generate data that’s regulatory compliant with the Alliance HPLC System, ideal for HPLC methods development and routine LC analysis.

  • Analytical Scale Purification System
    Analytical Scale Purification System

    Enjoy high-capacity sample processing and fraction collection at smaller preparative chromatography scales with a more efficient and cost-effective purification solution, the Analytical-Scale Purification System.

  • Arc HPLC System
    Arc HPLC System

    Count on the Waters Arc HPLC System for high-efficiency LC separations and quality data that meet your regulatory requirements with confidence.

  • Breeze QS HPLC
    Breeze QS HPLC

    For routine HPLC analysis with a choice of multiple components and simple-to-use software, the Breeze QS HPLC System delivers world-class performance – affordably.

  • LC Prep 150 System
    LC Prep 150 System

    Achieve rapid isolation and collection of your valuable samples with complete confidence with the LC Prep 150 System, the perfect fit-for-purpose solution.

  • LC Prep AutoPurification System
    LC Prep AutoPurification System

    Achieve flexible, scalable preparative LC configurations with the specificity of mass- directed purification or inclusiveness of UV detection with the LC Prep AutoPurification System.

  • Modular Systems
    Modular Systems

    Simplify your analytical to semi-preparative chromatography purification workflow and purify your compounds easier with Waters Modular Systems.

  • PATROL UPLC Process Analysis System
    PATROL UPLC Process Analysis System

    Access real-time, chromatographic-quality analysis for in-process samples with the PATROL UPLC Process Analysis System..

  • SFC Prep 150 AP System
    SFC Prep 150 AP System

    The SFC Prep 150 AP System is a preparative SFC system that provides routine compound purification for drug discovery labs using MassLynx Software with FractionLynx Application Manager.

  • SFC Prep 150 Mgm System
    SFC Prep 150 Mgm System

    Designed for high-throughput, semi-prep to preparative scale purifications, the SFC Prep 150 Mgm System is made for repeat injection (bulk purification) of chiral and achiral compounds.

  • SFC Prep 350 System
    SFC Prep 350 System

    Waters SFC Prep 350 System for bulk-scale supercritical fluid chromatography (SFC) sample purification easily allows you to purify a large amount of one sample.

  • Waters Fraction Collector III
    Waters Fraction Collector III

    Precisely perform fraction collection in chromatography with the easy-to-use Waters Fraction Collector III. Use it alone or as part of a Waters sample purification system for even greater sample collection capacity.

  • Waters Fraction Manager - Analytical
    Waters Fraction Manager - Analytical

    Efficiently isolate and recover small samples for additional analyses and increase recovery with the Waters Fraction Manager, a fraction collector designed for use with UPLC systems.

Chromatography Systems

Waters chromatography systems are designed to meet the diverse needs of laboratories, offering reliable and precise performance across a range of applications. These systems provide cutting-edge technology that enhances the speed, sensitivity, and accuracy of liquid chromatography (LC) and ultra-performance liquid chromatography (UPLC) analyses. Whether you are conducting routine analyses or more complex separations, Waters systems deliver the performance and flexibility needed for high-quality results in various fields such as pharmaceuticals, environmental testing, and food safety.

A popular option within Waters" lineup is the ACQUITY UPLC System, renowned for its ability to push the boundaries of performance in liquid chromatography. The ACQUITY UPLC system is designed for high-throughput labs that require faster run times and higher resolution without sacrificing data quality. By utilizing smaller particles in the column, the system achieves sharper peaks and increased sensitivity. This enhanced resolution is particularly beneficial in applications such as pharmaceutical analysis, where distinguishing between closely related compounds is critical. The ACQUITY UPLC system is also designed for robustness, allowing it to handle the high pressures and fast flow rates typically associated with UPLC methods, making it a powerful tool for any lab requiring top-tier performance.

For labs requiring a versatile system that can handle a broad range of applications, the Alliance HPLC System is another standout choice. Known for its dependability and ease of use, the Alliance HPLC system provides precise and consistent results, making it ideal for routine analysis and quality control. Its modular design allows for easy integration with various detectors and accessories, enabling it to be tailored to specific laboratory needs. The system"s advanced fluidics and sample management capabilities ensure smooth operation and reliable results, even for demanding workflows. The Alliance HPLC System is a trusted workhorse in many labs, offering the reliability needed for day-to-day operations across industries like pharmaceuticals, environmental testing, and manufacturing.

For those looking to maximize efficiency, the Arc HPLC System offers a balance of performance and cost-effectiveness. It is engineered to deliver high-quality separations while maintaining operational simplicity. With easy method transfer from older HPLC systems, the Arc HPLC system allows labs to upgrade their technology without disrupting existing workflows. It also features advanced sample preparation capabilities and robust hardware, making it a valuable asset in laboratories that require efficient, reliable, and versatile liquid chromatography solutions.

Waters chromatography systems are further complemented by intuitive software like Empower, which is designed to simplify data acquisition, processing, and reporting. This software helps laboratories improve productivity by streamlining workflows and providing real-time insights. Empower is a powerful tool for labs seeking to manage complex datasets and maintain compliance with industry regulations. Paired with Waters" hardware, it enhances the overall performance and usability of chromatography systems, ensuring that users can focus on generating high-quality data rather than managing operational complexities.

These chromatography systems are trusted by laboratories worldwide for their precision, flexibility, and innovative design. Whether you require the speed and sensitivity of the ACQUITY UPLC System or the dependability of the Alliance HPLC System, Waters has a solution to fit your specific needs. These systems not only enhance laboratory efficiency but also help deliver consistent, high-quality results across a wide range of applications.

Chromatography Systems FAQs

1.How do I choose the right Waters chromatography system for my lab"s needs?
Choosing the right Waters chromatography system depends on your lab's specific requirements. It"s best to evaluate your lab"s sample throughput, sensitivity needs, and existing workflows to determine which system will provide the most value.

2.Can I easily transfer methods from an older HPLC system to a new Waters system?
Yes, Waters chromatography systems are designed with method transfer in mind. The Arc HPLC system, in particular, is built to allow seamless method transfer from older HPLC systems. This ensures that labs can upgrade their technology without disrupting existing workflows, saving time and preserving validated methods.

3.Are Waters chromatography systems compatible with various column types?
Waters chromatography systems are highly versatile and compatible with a wide range of column types. Whether you're using traditional HPLC columns or more advanced UPLC columns with smaller particle sizes, these systems can accommodate different column chemistries and dimensions to suit various analytical needs. This flexibility makes them ideal for diverse applications across multiple industries.