MaxPeak Premier Columns

MaxPeak Premier Columns

See all of your sample with MaxPeak Premier Columns, the most universal column platform for chromatographers who need to reduce variability risks and save time, all while increasing recovery and sensitivity.

See all of your sample with MaxPeak Premier Columns, the most universal column platform for chromatographers who need to reduce variability risks and save time, all while increasing recovery and sensitivity.

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Closeup of a hand adjusting a column's yellow fob in an Arc Premier system

Non-specific adsorption (NSA) of metal sensitive compounds is an unpredictable challenge, leading to long column passivation times, chromatography with large relative standard deviations (RSDs), and broad peaks that can be a challenge to detect.

See and do more with MaxPeak Premier Columns, which utilize the latest progressive integrated technologies like MaxPeak High Performance Surfaces (HPS) to effectively reduce non-specific adsorption (NSA) losses due to metal interactions.

With MaxPeak Premier Columns, your lab can reduce the time wasted on column passivation and method optimization, while increasing reproducibility, sensitivity, and overall quality of results. Are you ready to see what you've been missing?

Learn about our complete MaxPeak Premier Solutions.

ACQUITY Premier Columns
Achieve increases in sensitivity and analyte recovery while reducing column passivation time and mitigating unwanted analyte/surface interactions with ACQUITY Premier Columns.

Atlantis Premier Columns
Discover Atlantis Premier Columns for high-performance liquid chromatography, designed to improve peak shape while mitigating unwanted interactions.

CORTECS Premier Columns
Eliminate doubt in UPLC, UHPLC, and HPLC analysis applications with CORTECS Premier Columns, designed to increase sample throughput while providing reproducible data for all analytes.

XBridge Premier Columns
Experience XBridge Premier HPLC and UHPLC Columns, designed to operate under extreme temperatures and mobile-phase pH while mitigating unwanted analyte/surface interactions.

XSelect Premier Columns
Discover XSelect Premier HPLC and UHPLC Columns designed to improve peak shape and maximize selectivity while mitigating unwanted analyte/surface interactions.

MaxPeak Premier Protein SEC Columns
Enhance your workflow with MaxPeak Premier Protein SEC Columns, size-exclusion chromatography columns for the characterization of proteins and peptides.

BioResolve Premier Columns
Increase intact and subunit protein recovery, improve charge variant resolution, and enhance LC & LC-MS sensitivity with Waters BioResolve Premier Columns, reversed-phase and ion exchange columns for bioseparation applications.

Application Specific Columns

MaxPeak Premier Columns for Oligonucleotide Analysis
Suited for the analysis of detritylated oligonucleotides using ion-pair, reversed-phase chromatography.

MaxPeak Premier Columns for Protein Analysis
Improves sensitivity for phosphorylated proteins and low-level intact and subunit mAb analysis with MaxPeak Premier Protein Columns. Tolerate extreme pH and temperature, and provides minimal secondary interactions.

MaxPeak Premier Columns for Glycan Analysis
Suited for analyzing released and 2-aminobenzamide (2-AB) labeled N-linked glycans from various biotherapeutics, as well as, for the HILIC analysis of neutral and acidic glycans.

MaxPeak Premier Columns for Peptide Analysis
Suited for the reversed-phase analysis of hydrophobic and hydrophilic peptides at low and high pH with outstanding peak capacity and peak shape in TFA or FA.

MaxPeak Premier Columns for Gene-Based Therapeutics
Analyze gene therapeutics to learn about the potency and safety of your sample with Waters Gene Therapeutics (GTx) Size-Exclusion Chromatography (SEC) Columns, designed to provide accurate, high-throughput data.
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MaxPeak Premier Columns are recognized for their leadership in chromatography column technology, spearheaded by Waters Corporation. These columns are meticulously designed to excel in both High-Performance Liquid Chromatography (HPLC) and Ultra-High-Performance Liquid Chromatography (UHPLC) applications.

At the core of MaxPeak Premier Columns are sophisticated design and manufacturing methodologies, ensuring exceptional reproducibility, resolution, and sensitivity in analytical separations. Constructed from high-quality materials, these columns undergo stringent quality control procedures to uphold consistent performance batch after batch.

Key features of MaxPeak Premier Columns include:

Precision Packing Technology: The stationary phase material within MaxPeak Premier Columns is precisely packed to optimize efficiency and resolution, resulting in sharper peaks and improved separation of analytes, even under the high flow rates typical of UHPLC systems.

Engineered Surface Chemistry: The columns' surface chemistry is carefully engineered to minimize undesirable interactions between analytes and the column material. This minimizes peak tailing and enhances peak shape, facilitating precise quantification and identification of compounds.

Versatile Application Range: MaxPeak Premier Columns demonstrate versatility across various applications, including pharmaceuticals, environmental analysis, and food and beverage testing. They are compatible with different mobile phases and sample matrices, accommodating diverse chromatographic requirements.

Long-lasting Durability: MaxPeak Premier Columns are designed to endure the demanding conditions of high-throughput laboratories, maintaining exceptional performance without compromise. With proper care and maintenance, they exhibit remarkable durability and consistency over prolonged periods.

Comprehensive Support: Waters Corporation provides extensive technical support to optimize the use of MaxPeak Premier Columns. This includes application guidance, troubleshooting assistance, and educational resources, enabling chromatographers to efficiently achieve their analytical goals.

In summary, MaxPeak Premier Columns represent a cutting-edge solution for chromatographic separations, offering researchers and analysts unparalleled levels of performance and reliability in their analytical workflows.

MaxPeak Premier Columns

1.What types of analytes are MaxPeak Premier Columns suitable for?
MaxPeak Premier Columns are designed for a wide range of analytical applications and can accommodate diverse types of analytes. They are particularly effective in the analysis of peptides and proteins, making them ideal for research in proteomics, biopharmaceuticals, and clinical studies due to their high efficiency and excellent peak shapes.
Additionally, these columns perform well with small molecules such as pharmaceuticals, environmental contaminants, and food additives. Beyond these, MaxPeak Premier Columns are suitable for analyzing various biomolecules, including nucleic acids, carbohydrates, and lipids. Their ability to handle polar compounds with minimal retention and tailing further enhances their uses, especially when separating challenging compounds that are difficult to analyze with traditional HPLC columns.

2.What are the recommended mobile phases for MaxPeak Premier Columns?
The optimal mobile phase for MaxPeak Premier Columns depends on the specific analytes and desired separation. However, these columns are compatible with a wide range of aqueous and organic mobile phases, offering flexibility in method development. Water-based mobile phases are commonly used for analyzing polar compounds such as peptides and proteins, with buffers like phosphate or acetate often added to control pH and improve peak shape.
Organic solvents like acetonitrile, methanol, and tetrahydrofuran (THF) are used to enhance the solubility of nonpolar analytes. Additionally, mixed mobile phases, which combine aqueous and organic solvents, are frequently a good option to achieve optimal separation for analytes with varying polarities.

3.What is the typical column lifetime for MaxPeak Premier Columns?
The lifespan of MaxPeak Premier Columns can vary depending on several factors, including usage frequency, sample matrix complexity, mobile phase composition, and storage conditions. More frequent use, complex or contaminated samples, and aggressive mobile phases can all contribute to shortening the column's life. However, with proper care and maintenance, including adhering to recommended cleaning and storage procedures, avoiding excessively high flow rates, and regularly monitoring performance, MaxPeak Premier Columns can provide reliable and long-term performance.